lexA Smed_1353 MLTRKQQELLLFIHERMKESGVPPSFDEMKDALDLASKSGIHRLITALEERGFIRRLPNRARALEVIKLPEAYAGNPQVRRGFSPSVIEGSLGKPAAPAPAPKPAPPAENASVVVPVMGRIAAGVPISAIQNNMHDISVPIEMIGSGEHYALEIKGDSMIEAGILDGDTVIIRNASTASIGDIVVALIDDEEATLKRFRRKGASIALEAANPAYETRIFGPDRVKIQGKLVGLIRRYH LexA repressor LEXA_SINMW 238 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, recA interacts with lexA causing an autocatalytic cleavage which disrupts the DNA-binding part of lexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity).